YuLab-SMU / biomedical-knowledge-mining-book

:books: Biomedical knowledge mining using GOSemSim and clusterProfiler
https://yulab-smu.top/biomedical-knowledge-mining-book/
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GSEA with phenotype permutation #13

Open NhatLe-github opened 2 years ago

NhatLe-github commented 2 years ago

Dear Yu,

I'm Dr. Nhat Le, a biostatistician/bioinformatics from OUCRU Vietnam.

Could you please incorporate phenotype permutation into your GSEA function? I think since the input gene list can be ordered in any kind of measure. For generality, you could allow the user to input a matrix of permutated data. Each column for one permutation. It means that users do the permuation by themself.

This would make the GSEA function complete. I would love to hear your opinion.

Thanks and cheers, Nhat