What are the meanings of qvalue, rank, leading_edge and core_enrichment in the result of GSEA using clusterProfiler?

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What are the meanings of qvalue, rank, leading_edge and core_enrichment in the result of GSEA using clusterProfiler? #302

Open JiahuaQu opened 3 years ago

JiahuaQu commented 3 years ago

Hi, I used "gseGO_CC_result <- as.data.frame(gseGO_CC)" to obtain the result of GSEA. In the data.frame, there are several colums which I don't understand. For example, rank, leading_edge and core_enrichment, especially the rank column.

In addition, there is the qvalue which we don't need set pAdjustMethod to obtain, but can't be used in plotting. What's the meaning or importance of qvalue?

Thank you.

Birendra-Kumar-S commented 6 months ago

Please check with this link: https://www.gsea-msigdb.org/gsea/doc/GSEAUserGuideTEXT.htm#_Running_a_Leading_Edge%20Analysis:~:text=reproducing%20analysis%20results.-,Detailed%20Enrichment%20Results,-From%20the%20Enrichment