Closed llrs closed 7 years ago
> require(clusterProfiler)
Loading required package: clusterProfiler
Loading required package: DOSE
DOSE v3.0.9 For help: https://guangchuangyu.github.io/DOSE
If you use DOSE in published research, please cite:
Guangchuang Yu, Li-Gen Wang, Guang-Rong Yan, Qing-Yu He. DOSE: an R/Bioconductor package for Disease Ontology Semantic and Enrichment analysis. Bioinformatics 2015, 31(4):608-609
clusterProfiler v3.2.10 For help: https://guangchuangyu.github.io/clusterProfiler
If you use clusterProfiler in published research, please cite:
Guangchuang Yu., Li-Gen Wang, Yanyan Han, Qing-Yu He. clusterProfiler: an R package for comparing biological themes among gene clusters. OMICS: A Journal of Integrative Biology. 2012, 16(5):284-287.
> data(geneList)
> de = names(geneList)
> de = names(geneList)[1:100]
> x = enrichKEGG(de)
> x
#
# over-representation test
#
#...@organism hsa
#...@ontology KEGG
#...@keytype kegg
#...@gene chr [1:100] "4312" "8318" "10874" "55143" "55388" "991" ...
#...pvalues adjusted by 'BH' with cutoff <0.05
#...3 enriched terms found
'data.frame': 3 obs. of 9 variables:
$ ID : chr "hsa04110" "hsa04114" "hsa04115"
$ Description: chr "Cell cycle" "Oocyte meiosis" "p53 signaling pathway"
$ GeneRatio : chr "8/41" "6/41" "4/41"
$ BgRatio : chr "124/7176" "124/7176" "69/7176"
$ pvalue : num 3.76e-07 6.46e-05 6.06e-04
$ p.adjust : num 3.72e-05 3.20e-03 2.00e-02
$ qvalue : num 3.48e-05 2.99e-03 1.87e-02
$ geneID : chr "8318/991/9133/890/983/4085/7272/1111" "991/9133/983/4085/51806/6790" "9133/6241/983/1111"
$ Count : int 8 6 4
#...Citation
Guangchuang Yu, Li-Gen Wang, Yanyan Han and Qing-Yu He.
clusterProfiler: an R package for comparing biological themes among
gene clusters. OMICS: A Journal of Integrative Biology
2012, 16(5):284-287
I can't reproduce your issue, and thanks for pointing out the example.
Strange, after three trials I finally could print the description. It might be a problem with my setup... Thanks for your quick response
and also might be a problem of the KEGG web site.
In the recent versions of clusterProfiler I have found that all my pathways are NA see:
Also, have a look at the example, it doesn't return any significant pathway, which may not be what you wanted to show :D