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Yves-CHEN / DENTIST

DENTIST (Detecting Errors iN analyses of summary staTISTics) is a QC tool for summary-data-based analyses.
GNU Lesser General Public License v3.0
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Passing R to DENTIST #13

Open pcarbo opened 2 years ago

pcarbo commented 2 years ago

Hi authors of DENTIST: I would like to check consistency between my SNP-level summary statistics (z-scores) and an LD correlation matrix (R) obtained from a reference panel. Is there a way to pass R as input to DENTIST without having to provide the individual-level data?

Yves-CHEN commented 2 years ago

Yes. It is a good idea to store LD matrix(R) and use R over the individual-level data. In fact, some efforts were made to store LD matrix in a storage-efficient manner, but the function has not been fully implemented yet. It will take quite some more to time to make it.

pcarbo commented 2 years ago

@Yves-CHEN Thanks for clarifying!

MalteThodberg commented 1 year ago

@Yves-CHEN has this feature been implemented yet?

yanyul233 commented 1 year ago

Also eager to have this feature