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ZFIN / zebrafish-anatomical-ontology

Ontology describing the anatomy of Danio rerio from a single cell to adult fish. The namespace of the ontology is zebrafish_anatomical_ontology the prefix is ZFA. Updates to ZFA are released every other month. A subset of the ZFS http://purl.obolibrary.org/obo/zfs.obo is packaged with this ontology.
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Possible NTR: anterior segment mesenchyme (ASM) #178

Open LeylaR opened 4 months ago

LeylaR commented 4 months ago

Should anterior segment mesenchyme be added to the AO? The anterior segment mesenchyme derives from the periocular mesenchyme (POM) and gives rise to some components of the anterior segment (AS). Anterior segment mesenchyme is described and characterized in 3 publications (PubMed IDs 32528955, 36563566, 37024546) from the Famulski lab:

Van Der Meulen, K.L., Vöcking, O., Weaver, M.L., Meshram, N.N., Famulski, J.K. (2020) Spatiotemporal Characterization of Anterior Segment Mesenchyme Heterogeneity During Zebrafish Ocular Anterior Segment Development. Frontiers in cell and developmental biology. 8:379. https://zfin.org/ZDB-PUB-200613-8 PMID 32528955

Vöcking, O., Van Der Meulen, K., Patel, M.K., Famulski, J.K. (2022) Zebrafish anterior segment mesenchyme progenitors are defined by function of tfap2a but not sox10. Differentiation; research in biological diversity. 130:324232-42. https://zfin.org/ZDB-PUB-221224-39 PMID 36563566

Vöcking, O., Famulski, J.K. (2023) A temporal single cell transcriptome atlas of zebrafish anterior segment development. Scientific Reports. 13:56565656. https://zfin.org/ZDB-PUB-230407-53 PMID 37024546

cerivs commented 1 month ago

Maybe. Anterior segment mesenchyme would develop from periocular mesenchyme. POC should have relationship with some cranial nnc if we make the ASM term so we can have development tree. Def from ZDB-PUB-230407-53 ASM is composed of POM cells which have committed to the AS fate and migrated to the AS space.