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ZW-xjtlu / exomePeak2

Peak calling and differential methylation for MeRIP-Seq
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Question about filters on Differential methylated peaks #14

Open serpei opened 2 years ago

serpei commented 2 years ago

Good morning, I have a question about filters that have to be applied on differential methylation results. Default filters peaks that have pvalue>0.0001, nevertheless also padj is evaluated. So my question is: why did you choose pvalue? And it is better to use pvalue or adjusted pvalue? Thank you, Serena

wangyuhu123 commented 9 months ago

Have you solved this problem?

serpei commented 9 months ago

Hi, not really. I only saw the distribution of pvalues and p-adjusted and I decided to keep p values because using p-adjusted I had only few results. S