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ZijieJin / scFusion

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Would it be available on 10X? #8

Closed byemypast closed 2 years ago

byemypast commented 2 years ago

Thank you for your great work! I am trying to utilize the scFusion in my scRNA data. However, I found the software was developed under the protocol of smart-seq2. I wonder whether it could be used on my 10x-based scRNA data?

Thx, Junyi

ZijieJin commented 2 years ago

Indeed, we developed scFusion for Smart-Seq protocols rather than droplet-based 10X. You can run scFusion on your 10X data, but the performance may be not good. We optimized the model using the dense Smart-Seq data, since 10X data is sparse, many true gene fusions might be missed.

byemypast commented 2 years ago

Thanks for your kindly support! Have a nice day :D