There seems to be a couple issues with extensions that are in a disabled state:
A profile is not saved with disabled extensions. This might be as intended, since it doesn't really make sense to load a profile with disabled extensions (you would just create another profile with those extensions enabled). But, it could be unexpected, causing disabled extensions to get wiped, potentially a problem if you don't remember which extensions those were.
If you install an extension and disable it on one profile, then switch to another profile that has that extension enabled, the extension remains disabled.
There seems to be a couple issues with extensions that are in a disabled state:
A profile is not saved with disabled extensions. This might be as intended, since it doesn't really make sense to load a profile with disabled extensions (you would just create another profile with those extensions enabled). But, it could be unexpected, causing disabled extensions to get wiped, potentially a problem if you don't remember which extensions those were.
If you install an extension and disable it on one profile, then switch to another profile that has that extension enabled, the extension remains disabled.