aarsonline / aarsonline.github.io

AARS Online - an interactive database of aminoacyl-tRNA synthetase sequences, structures, and taxonomy
GNU General Public License v3.0
1 stars 0 forks source link

Valine has the most error prone codons #58

Closed jordandouglas closed 3 months ago

jordandouglas commented 9 months ago

A mass spec studied suggests that V -> M,I,L,A are among the most common mistranslation events in E.coli, and V -> A,I,L,P in yeast

This fun fact should be incorporated into the introduction on ValRS

https://doi.org/10.1016/j.molcel.2019.06.041 Systematic Detection of Amino Acid Substitutions in Proteomes Reveals Mechanistic Basis of Ribosome Errors and Selection for Translation Fidelity