Closed Prabhu89-code closed 1 year ago
999 for the dn/ds ratio is probably due to lack of synonymous differences. it's a bit like tossing a coin 5 or 10 times and observing no heads, so the probabilty of heads will be estimated to be 0. the likelihood ratio test is fine. but you should not interpret the dn/ds ratio literally. best, ziheng
Dear Dr. Yang, I agree you have answered several times about this issue in google_groups. Can you kindly clarify by doubt on how to interpret this ratio whether branch with #999 is error or it can be a positive selection ?
Thanking you!
Regards, Dr. Prabhakaran S, Scientist, NIPGR.