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abyzovlab / CNVpytor

a python extension of CNVnator -- a tool for CNV analysis from depth-of-coverage by mapped reads
MIT License
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Question about bin size and bam file #216

Open oceancongliu opened 5 months ago

oceancongliu commented 5 months ago

Hello, I'm planning to analyze one groups of samples with a sequencing depth of about 10 x.

My question is, what is the suitable setting for my bin size? 3k or 1k ? And, Whether the files generated from the BWA need to be sorted or not (samtools sort)?

Thanks.