metaDEGth: meta-analysis of Differentially Expressed Genes using parametric, empirically-derived P-value distributions
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Perform checks for other P value distributions #12
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adamsardar opened 5 years ago
It would be good if the routines spat out an error when an incorrect P-value distribution was provided.
Internally this would probably look like a goodness-of-fit test between a variety of alternative models (bimodal, uniform, right skew mixture etc.).
Probably could start with the P-value oddities described here: http://varianceexplained.org/statistics/interpreting-pvalue-histogram/