adamsardar / metaDEGth

metaDEGth: meta-analysis of Differentially Expressed Genes using parametric, empirically-derived P-value distributions
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Explore work on extensions to Fisher's method #14

Open adamsardar opened 5 years ago

adamsardar commented 5 years ago

A bit of a fact finding mission. The wikipedia page makes method of combination of non-independent P-values. Might be worth exploring.

https://en.wikipedia.org/wiki/Extensions_of_Fisher%27s_method

https://www.sciencedirect.com/science/article/pii/S0167715202003103?via%3Dihub