Closed jcgrenier closed 4 years ago
Hi, you can concatenate all the chromosomes, it is not a problem and will result in a normal looking sample.
Best, Apostolos
Hello @adimitromanolakis , thanks for the quick answer! I'll give it a try and will come back to you if we are encountering any issues with that! Thanks!
Hum, while thinking about it, how does it work exactly. How is one samples simulated? Does it take 2 different samples as parents of the samples and create a new one, or it's more random than this?
Thanks for your help!
Depends, if you simulate independant samples then there are no parents but generated randomly based on a model of the LD and allele frequencies of the markers. If you generate family data, then 2 individuals have to be the parents.
Alright, that's basically what I wanted to do. Thanks a lot for your help!
Hello! Thanks for that tool! Is there a way to directly simulate a whole sample that will have a genetic background that will look normal? The only thing I was able to do for the moment is to simulate chromosome per chromosome, so I suppose that I won't be able to concatenate all the chromosomes together in the end without looking at weird samples.
Thanks for the help. Best,