aerickso / SpatialInferCNV

Clone Calling from Visium Spatial Transcriptomics of Cancer samples
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Image based spatial data #12

Open SGIlabes opened 2 months ago

SGIlabes commented 2 months ago

Thank you for creating such a great tool. Does your tool work with CosMx and Xenium, not just Visium?

acjordan333 commented 2 weeks ago

This is a great question. I have been wondering this as well - I feel this could potentially work for CosMx data which has a very sparse coverage of the genome (~1000 probes and sometimes 6000 probes), but could technically still identify clones based on the probes that do exist (if there was a population of tumor cells with Kras or Myc amplifications, etc, that normal cells would not have).