aertslab / SCENIC

SCENIC is an R package to infer Gene Regulatory Networks and cell types from single-cell RNA-seq data.
http://scenic.aertslab.org
GNU General Public License v3.0
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Loosing too many genes #230

Closed charlesgwellem closed 2 years ago

charlesgwellem commented 2 years ago

Thank you for this great tool. I have a mouse single cell RNA seq data set, aligned with the mouse reference genome (mm10, Ensembl annotation release 91). The data set consists of ten thousand already filtered genes. But when I run correlation in SCENIC, I realise that only 500 TFs are present in my dataset. I think there should be more TFs in my data set. Is there a way I can fix this so I do not loose too many TFs?