what is the exact mean of superposition?

aertslab / SCope

Fast visualization tool for large-scale and high dimensional single-cell data

GNU General Public License v3.0

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what is the exact mean of superposition? #368

Closed sygongcode closed 4 years ago

sygongcode commented 4 years ago

Hello, everyone,

First, thank you for your nice work that helps me a lot with my project.

I have some questions when I using SCope to search for some genes' alteration in the fly brain in aging. I didn't find any contact information for help. So, I come here to ask for help. The question is that when I use the compare part, I found three options, Number of displays, Superposition(N/A, OR, AND), and Configuration, what is the exact mean of superposition? For example, If I drag age 3, and age 15, age 30 and age 50 in genotype W1118, male fly brain for comparison. And then I type a gene that I am interested in. after I select OR or AND in the superposition option, I got different plots. So, what are the exact means when I select OR or AND? Can anyone help me? Thank you.

Best regards,

Shangyu

dweemx commented 4 years ago

Hey @sygongcode , Superposition is a feature that is applying a logical operator (like in computer science) on the different set of cells from the annotation values that you have dragged onto a viewer. As an example, in your case,

Superposition(OR) with age 3, 15, 30, 50 and genotype W1118 will display all the cells that have at least one of these annotations.
Superposition(AND) with age 3, 15, 30, 50 and genotype W1118: will display you only the cells that have all these 5 annotations.

sygongcode commented 4 years ago

Hey @sygongcode , Superposition is a feature that is applying a logical operator (like in computer science) on the different set of cells from the annotation values that you have dragged onto a viewer. As an example, in your case,

Superposition(OR) with age 3, 15, 30, 50 and genotype W1118 will display all the cells that have at least one of these annotations.

Superposition(AND) with age 3, 15, 30, 50 and genotype W1118: will display you only the cells that have all these 5 annotations.

Thank you so much. Now I can confirm it.

Why I ask this question, is because I found some strange results. But maybe it is what it is. So, thank you again.

Best regards, Shangyu