pySCENIC is a lightning-fast python implementation of the SCENIC pipeline (Single-Cell rEgulatory Network Inference and Clustering) which enables biologists to infer transcription factors, gene regulatory networks and cell types from single-cell RNA-seq data.
The
grn
step uses sklearngradient boosting regularization
. Canxgboost
orlightgbm
be used instead? What are the parameters like?