aertslab / scenicplus

SCENIC+ is a python package to build gene regulatory networks (GRNs) using combined or separate single-cell gene expression (scRNA-seq) and single-cell chromatin accessibility (scATAC-seq) data.
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eRegulon difference between two groups in specific cell type #119

Closed ianhsu99 closed 1 year ago

ianhsu99 commented 1 year ago

Hi,

First of all, thanks for this excellent software.

I have a processed dataset with 13 cell types and two groups (disease and control). I want to see the regulon difference between the two groups in Fibroblasts.

I wondered if it makes sense to run the SCENIC+ on Fibroblasts and use groups (e.g. disease and control) as the variable for the run_scenicplus() function.

Cheers,

Ian