How changing the cell annotation influences the SCENIC+ inference?

aertslab / scenicplus

SCENIC+ is a python package to build gene regulatory networks (GRNs) using combined or separate single-cell gene expression (scRNA-seq) and single-cell chromatin accessibility (scATAC-seq) data.

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How changing the cell annotation influences the SCENIC+ inference? #160

Closed Priyadarshini-Rai closed 1 year ago

Priyadarshini-Rai commented 1 year ago

Please don't post an issue but post your issue in the discussions instead: https://github.com/aertslab/scenicplus/discussions

Thanks you :)

SeppeDeWinter commented 1 year ago

Hi,

For multiome data the cell annotation will not influence the eGRN inference. For non-multiome it will, because it is used to pair scATAC and scRNA-seq cells.

Best,

Seppe