aertslab / scenicplus

SCENIC+ is a python package to build gene regulatory networks (GRNs) using combined or separate single-cell gene expression (scRNA-seq) and single-cell chromatin accessibility (scATAC-seq) data.
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Subset regions from cistromes params and fix dotplot repressors #337

Open DanieFD opened 3 months ago

DanieFD commented 3 months ago

Added the "path to regions to subset" as a parameter in the snakemake config file. This allows giving the path to the bed file containing the MACS called peaks that one would like to subset when creating cistromes (hence, cell type-specific cistromes). It can also be left empty (empty string) if no regions should be subsetted.

Also, one small change in the regulons dotplot: considered all regulons with "-" as repressors.