aertslab / scenicplus

SCENIC+ is a python package to build gene regulatory networks (GRNs) using combined or separate single-cell gene expression (scRNA-seq) and single-cell chromatin accessibility (scATAC-seq) data.
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[API question] what is the difference between scplus_obj from "running scenic+ documentation" vs "created using GEX.h5ad+cistopic_obj in API"? #489

Closed yojetsharma closed 3 weeks ago

yojetsharma commented 1 month ago

I am trying to understand if there is there a difference in the scplus_obj after the snakemake pipeline by running the mudata_to_scenicplus vs the one created using the GEX.h5ad and cistopic_obj +menr? If there isn't then why are there these two different ways of making the scplus_obj?