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aertslab / scenicplus

SCENIC+ is a python package to build gene regulatory networks (GRNs) using combined or separate single-cell gene expression (scRNA-seq) and single-cell chromatin accessibility (scATAC-seq) data.
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Unpaired example #75

Closed Nusob888 closed 1 year ago

Nusob888 commented 1 year ago

Hi,

thanks for the great tool. Can I ask whether there are plans to include an unpaired example on the docs?

I do not have ATAC-seq, but my understanding is that I could theoretically use ATAC of immune cells from an unpaired dataset? However, there are no clear examples of how to do this.

Many thanks for your consideration

SeppeDeWinter commented 1 year ago

We have a tutorial using unpaired scATAC-seq and scRNA-seq in melanoma cell lines: https://scenicplus.readthedocs.io/en/latest/mix_melanoma_cell_lines.html

Is this what you are looking for?

Best,

Seppe