The analysis of several experimental designs would benefit from the ability to use multilevel/mixed effects models.
The variancePartition package adds support for multilevel/mixed effects models to limma (under the name of dream) and I am wondering whether it could be added as an option to lipidr.
The analysis of several experimental designs would benefit from the ability to use multilevel/mixed effects models.
The
variancePartitionpackage adds support for multilevel/mixed effects models tolimma(under the name ofdream) and I am wondering whether it could be added as an option tolipidr.https://diseaseneurogenomics.github.io/variancePartition/
Hoffman GE, Roussos P (2020). “dream: Powerful differential expression analysis for repeated measures designs.” Bioinformatics. doi:10.1093/bioinformatics/btaa687