After reviewing the "parts lists", is there anything we are missing (e.g. an object representing the TCR-pMHC complex; Antigen object)? Is there anything that is incomplete that we should fill out (e.g. Receptor object)? Are there any ontologies that we should be including? Are there ontologies terms that need expansion?
Gaps identified:
Currently difficult to identify when the same repertoire appears in multiple repositories of the ADC. Also difficulty to keep track when their are multiple processed repertoires deriving from different pipelines applying to the same starting repertoire. Need to resolve how we currently use identifiers to fix this.
Formalize strain and breed
How to handle the variety of assay types
We need to be more precise for terms like specificity, reactivity, affinity, etc.
New things identified:
The membrane-bound receptor for B cell, BCR, is different from the soluble Antibody protein, so we likely need to represent them differently.
After reviewing the "parts lists", is there anything we are missing (e.g. an object representing the TCR-pMHC complex; Antigen object)? Is there anything that is incomplete that we should fill out (e.g. Receptor object)? Are there any ontologies that we should be including? Are there ontologies terms that need expansion?
Gaps identified:
New things identified: