aksub99 / MolDQN-pytorch

A PyTorch Implementation of "Optimization of Molecules via Deep Reinforcement Learning".
MIT License
75 stars 28 forks source link

small molecules optimization #15

Open amir-tagh opened 3 years ago

amir-tagh commented 3 years ago

Hello,

I have some small molecules which interact with a rather high binding affinity toward my protein. I was wondering if I could use MolDQN to optimize these compounds and dock them against the protein target and see if the binding affinity has increased. I can not figure out how I can feed the "smi" of these compounds to the main.py and get the outputs. could you please provide an example on how I can achieve this?

Thanks in advance. Best, Amir