Question about trainning custom m6A model

al-mcintyre / mCaller

A python program to call methylation (m6A in DNA) from nanopore signal data

MIT License

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Question about trainning custom m6A model #5

Closed weir12 closed 5 years ago

weir12 commented 5 years ago

Hi, @al-mcintyre I tried to use your script to trianning my m6A R9.4 model.But I have noticed that I must provide a file which contain m6A pos and A pos in ref. Unlucky,I can't provide such completely methylated or canonical sites. Can I trainning the model by providing a set of methylated reads and non-methylated reads instead of input locations? Would you give me some tips about rebuilding your script if you like? thanks:)

al-mcintyre commented 5 years ago

Hi @weir12, I haven't implemented this feature yet, but it shouldn't be too difficult to do. There are a couple bugs but I will try to update soon to allow users to provide their own labelled tsv files for training.