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al2na / methylKit

R package for DNA methylation analysis
https://bioconductor.org/packages/release/bioc/html/methylKit.html
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uneven number of replicates #327

Closed LandiMi2 closed 3 weeks ago

LandiMi2 commented 2 months ago

Hello @alexg9010 . I do have an unbalanced number of replicates for my conditions. For example, one condition A has 5 replicates B - 3 and C - 4. Can methylKit handle these uneven numbers of replicates in calculating differential methylation?

al2na commented 2 months ago

It shouldn’t matter

Sent from mobile, excuse the brevity

On Mon, Sep 16, 2024 at 4:04 PM Michael Landi @.***> wrote:

Hello @alexg9010 https://github.com/alexg9010 . I do have an unbalanced number of replicates for my conditions. For example, one condition A has 5 replicates B - 3 and C - 4. Can methylKit handle these uneven numbers of replicates in calculating differential methylation?

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LandiMi2 commented 2 months ago

Great! I will give it a go.