alachins
commented
2 years ago we made some changes to the mu statistic in May 2019 to make it independent of the chromosome length and accounting for different sample sizes so I think that it is reasonable to do such comparison among different populations
On Sat, Apr 30, 2022 at 4:57 AM ymatmt @.***> wrote:
I read the recent genomics paper ( https://www.nature.com/articles/s41467-019-10972-w) and the paper compared the mu statistic among two population. I am wondering that is it reasonable to compare the mu statistic among populations. When it is reasonable, can we use a statistical test (such as non-parametric Wilcoxon test) in a specific region?
e.g. In chr1: 10000-20000, we get 10 mu statistic for each population. pop1 mu: 0.1, 4, 5, 6, 7, 10, 2, 3, 0, 0.1 pop2 mu: 10, 3, 5, 9, 15, 20, 21, 32, 10, 0.5
Then is it reasonable for doing Wilcoxon test among pop 1 and pop 2.
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ymatmt
I read the recent genomics paper (https://www.nature.com/articles/s41467-019-10972-w) and the paper compared the mu statistic among two population. I am wondering that is it reasonable to compare the mu statistic among populations. When it is reasonable, can we use a statistical test (such as non-parametric Wilcoxon test) in a specific region?
e.g. In chr1: 10000-20000, we get 10 mu statistic for each population. pop1 mu: 0.1, 4, 5, 6, 7, 10, 2, 3, 0, 0.1 pop2 mu: 10, 3, 5, 9, 15, 20, 21, 32, 10, 0.5
Then is it reasonable for doing Wilcoxon test among pop 1 and pop 2.