alevax / pyviper

Porting of Protein Activity and Pathway Inference to single cell and Python.
MIT License
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Compatibility with NA input values #72

Open alexanderlewis99 opened 1 month ago

alexanderlewis99 commented 1 month ago

New feature request:

Hi all, I realized there is an issue when input matrices contain NAs R viper just ommits NAs when computing protein activity but pyviper returns all NA (I know gene expression matrices don't have missing values, but exon inclusion matrices and proteomics have many). I am finishing the project using VIPER for splicing factors and as an example usage of the SF-exon networks with VIPER I am using R and python