amplab / snap

Scalable Nucleotide Alignment Program -- a fast and accurate read aligner for high-throughput sequencing data
https://www.microsoft.com/en-us/research/project/snap/
Apache License 2.0
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Extend Alt contigs option to allow mapping to two haplotypes genomes. #169

Open ghuls opened 8 months ago

ghuls commented 8 months ago

It would be great if the Alt contigs approach could be extended so SNAP could use two haplotype FASTA files with all chromosomes/contigs and assign better mapping qualities to reads that map to "multiple" places with the same score, but only once in each hapoltype.