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andrewhooker / PopED

Population Experimental Design (PopED) in R
https://andrewhooker.github.io/PopED/
GNU Lesser General Public License v3.0
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Irregular dosing #33

Open ahmedsuleiman opened 6 years ago

ahmedsuleiman commented 6 years ago

Hi Andrew,

Is it possible to introduce irregular dosing when creating the PopED database? E.g. switching from a loading dose to a maintenance dose, or having some irregular dosing intervals within the same group/arm.

Thanks a lot in advance.

Ahmed Suleiman

Anks2030 commented 3 years ago

Hi Ahmed, I also had the same question with @andrewhooker posted under below link https://github.com/andrewhooker/PopED/issues/56#issue-828466596

In an another case study the dosing was from same route sc, but I needed different loading and different maintenance dose so I used following code under # define initial conditions

dose_times = c(seq(from=0,to=336, by=84),seq(from=336,to=8568,by=TAU))