beta value of MatrixEQTL results

Zhangj215 commented 4 years ago

Hi Using MatrixEQTL R package, I am performing both cis and trans eQTL analyses in order to find some SNPs associated with some genes of interest. I try to understand the Beat value in the results, What does "Effect size estimate" mean here? I am wondering whether it can represent a trend in changes in gene expression levels in different genotypes.

andreyshabalin commented 4 years ago

The effect size estimate is the beta estimate from the linear regression of the gene on the SNP.

I hope this page brings some clearity: http://www.bios.unc.edu/research/genomic_software/Matrix_eQTL/CompareResults.html

Zhangj215 commented 4 years ago

Thank you very much, this is exactly the kind of thing I'm after. 发送自 Windows 10 版邮件https://go.microsoft.com/fwlink/?LinkId=550986应用

发件人: Andrey Shabalinmailto:notifications@github.com 发送时间: 2020年4月14日 12:46 收件人: andreyshabalin/MatrixEQTLmailto:MatrixEQTL@noreply.github.com 抄送: jiZhangmailto:zhangj_wmu.edu@outlook.com; Authormailto:author@noreply.github.com 主题: Re: [andreyshabalin/MatrixEQTL] beta value of MatrixEQTL results (#10)

Closed #10https://github.com/andreyshabalin/MatrixEQTL/issues/10.

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andreyshabalin / MatrixEQTL

beta value of MatrixEQTL results #10