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andyrimmer / Platypus

Platypus Variant Caller
GNU General Public License v3.0
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Merge gVCFs (N+1 Calling) #29

Open andyrimmer opened 10 years ago

andyrimmer commented 10 years ago

Platypus should be able to produce gVCFs for many individual samples, and then merge them to create a single VCF with appropriate genotypes across all samples. This is an alternative to joint calling on many samples, and should be much cheaper. Since Platypus can already output gVCF, it's only the merging that needs doing.

andyrimmer commented 10 years ago

N.B. Need to be careful with complex alleles and multi-allelic records.