angelolab / ark-analysis

Integrated pipeline for multiplexed image analysis
https://ark-analysis.readthedocs.io/en/latest/
MIT License
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Make row sum normalization optional for pixel-level Pixie preprocessing #1140

Open alex-l-kong opened 1 month ago

alex-l-kong commented 1 month ago

What is the purpose of this PR?

@kxleow would like to verify if turning off row sum normalization will help with running a MALDI slide through Pixie.

How did you implement your changes

Add a flag rowsum_norm that defaults to True but can be set to False in the notebook.

Remaining issues

This feature will not be merged if the results end up looking worse.

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