Modify and save?

[dakami]

Any easy path to manipulating the loaded state and saving a new binary?

[zardus]

Check out patcherex (https://github.com/shellphish/patcherex); that's what we used in the CGC. It's a binary rewriting framework based on angr, though it might be a bit too heavyweight, depending on what your needs are.

[dakami]

Yup, that'll do