N.B. Need to carefully select TCRs and cognate antigens validated by dextramer-sorting + expansion (Isolation and expansion of antigen-specific CD8+ T cells in Methods) and cloning/stimulation (TCR reactivity validation in Methods) from Suppl Info and Source Data. Also check if there is some structural data there.
Schmidt J et al. Neoantigen-specific CD8 T cells with high structural avidity preferentially reside in and eliminate tumors. Nat Comm 2023