Open arkhan19 opened 2 years ago
Hey! This might be expected as if you tick both TRA
and TRB
there still might be some entries that do not satisfy other filters. In contrast, paired gene export is ignoring any other filters you specified. If you are sure this is not the case, you can try to diff
your results and give a bit of more context here so we can figure it out together.
@f3n1Xx For example, does the output match for you if you go to the Meta
filters panel and tick both Include non-canonical
and Include unmapped V/J
filter options?
I have filtered mouse and human species with both TRA and TRB selected. No other filter were changed.
@f3n1Xx For example, does the output match for you if you go to the
Meta
filters panel and tick bothInclude non-canonical
andInclude unmapped V/J
filter options?
my samples increased by 2 thousand
I have filtered mouse and human species with both TRA and TRB selected. No other filter were changed.
Yes, but there are some other filters that are enabled by default (as I mentioned, Include non-canonical
as an example).
my samples increased by 2 thousand
Can you check if you still have different results with ticked Include non-canonical
and Include unmapped V/J filter
filters? In my case if I select TRA
and TRB
for mouse and human species and tick both Include non-canonical
and Include unmapped V/J filter
- Include paired
export option does not make any difference in number of samples.
@f3n1Xx By default vdjdb.cdr3.net does not show and does not return you spurious CDR3 sequences (unless you explicitly enable this), but "export paired" option ignores this setting and returns you all available data no matter spurious it or not.
So I would say what you observe is an expected behaviour and your exported data should have some extra entries that are not included by default.
Paired gene export is giving different results than expected. I have selected both TRA and TRB in filters. What exactly is the function of this option, I am getting a different number of samples in either case.
What I am doing:
What I am getting: When Paired gene export is enabled:
When Paired gene export is disabled:
What is expected: I am under the impression that there might be some data whose pair isn't available, and their population must be more than the data whose pair is available. Why am I getting more samples when the option is enabled? This issue is just based on intuition, i haven't checked the code.