Thanks for the magic tool. I have used the trio bin method to generate a haplotype-resolved assembly, which includes two haplotypes (hap1 and hap2). I'm now wondering whether it would be better to polish these two haplotypes together (merge as one fasta) or separately by splitting the reads (HiFi).
Hi,
Thanks for the magic tool. I have used the trio bin method to generate a haplotype-resolved assembly, which includes two haplotypes (hap1 and hap2). I'm now wondering whether it would be better to polish these two haplotypes together (merge as one fasta) or separately by splitting the reads (HiFi).
Gong