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araskind / MRC2Toolbox

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Entropy Score as an export option #4

Open Brady-Anderson opened 2 years ago

Brady-Anderson commented 2 years ago

Entropy score is calculated for potential database matches but is not an exportable option. Could this be added for those who need to export results to external software like R for tabulating ID numbers?

Brady-Anderson commented 2 years ago

Furthermore, could IDs be reordered to have the top entropy score be listed first similarly to how top in source or hybrid hits can be assigned over identity hits?

araskind commented 2 years ago

I am not exactly sure what you mean by "reorder". If it is just when you go through the entries in GUI, you can simply sort the ID table by entropy score in descending order. Or do you want to batch-assign best entropy score as default ID?

Brady-Anderson commented 2 years ago

Hi Sasha,

I was referring to this button where you can "Set up default MSMS library match re-assignment". [image: Screen Shot 2022-05-02 at 10.53.21 AM.png]

My understanding is that library hits are initially ranked/assigned by whatever the top Scoring entries are. I think it'd be cool to allow the user to choose whichever metric they want to rank their hits by (Dot product, reverse dot product, entropy score). I know this button right now reorders entries by match type but could it be expanded to reorder entries by a different scoring metric fairly easily? If not, don't worry about it.

I haven't done an exhaustive dive into looking at how the entropy score compares to NIST score yet, but overall I have been more impressed with it than just a score threshold of 500 or something similar. I'd love to reorder the top hit for comparison sake to that with the highest entropy score to further investigate it.

On Mon, May 2, 2022 at 10:13 AM Sasha Raskind @.***> wrote:

I am not exactly sure what you mean by "reorder". If it is just when you go through the entries in GUI, you can simply sort the ID table by entropy score in descending order. Or do you want to batch-assign best entropy score as default ID?

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