Sub-groups for beta-lactam antibiotics

arpcard / amr_curation

A public repository for collective curation of antimicrobial resistance (AMR) genes and mutations. Submit, discuss, and resolve AMR curation issues.

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Sub-groups for beta-lactam antibiotics #100

Closed agmcarthur closed 4 days ago

agmcarthur commented 6 months ago

CARD is starting to curated sub-families of beta-lactamases into the ARO, but we should also start to curate sub-groups of beta-lactams, e.g., more specific groupings than just cephalosporin. Starting this issue to spur us to review current classifications.

agmcarthur commented 6 months ago

Examples: functional group (monobactams, penicillins, early (1st-2nd generation) cephalosporins, extended-spectrum (3rd-generation) cephalosporins, carbapenems, 4th generation cephalosporin cefepime, 5th generation cephalosporin ceftaroline, siderophore cephalosporin cefiderocol, and all beta-lactamase plus inhibitor combinations

agmcarthur commented 6 months ago

See https://atcddd.fhi.no/atc_ddd_index/?code=J01D&showdescription=no and https://msberends.github.io/AMR/articles/datasets.html#antibiotics-antibiotic-antifungal-drugs

agmcarthur commented 4 days ago

Draft being presented to AMRrules consortium, with intended December 2024 release.