aryarm / as_analysis

A complete Snakemake pipeline for detecting allele specific expression in RNA-seq
MIT License
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preliminary support for allele specific open chromatin (ASOC) analyses #62

Closed aryarm closed 3 years ago

aryarm commented 3 years ago

by substitution of ATAC-seq for RNA-seq within the WASP subworkflow (see #61)

Note: this PR does not add support for ASOC within the variant calling subworkflow. In the future, we might be able to use VarCA for this.

This PR also allows users to provide VCFs that do not have the requisite GQ tags, as long as they provide a default GQ value in the configuration. We recommend a value of 20, a pretty conservative estimate. These changes resolve #60