aryeelab / hichipper

A preprocessing and QC pipeline for HiChIP data
MIT License
33 stars 12 forks source link

hichipper into .hic file #76

Open AnaAzambuja opened 5 years ago

AnaAzambuja commented 5 years ago

Hi, I am using hichipper and diffloop to analyse my H3K27Ac HiChip data. Is that a way to convert hichipper output into .hic file for JuiceBox visualization?

Thanks, Ana

caleblareau commented 5 years ago

Hi @AnaAzambuja, if you want to use Juicebox, then Hichipper isn't necessarily required for this (since it is subsetting the interactions to defined anchors whereas HiC keeps the full contact matrix). I'd recommend converting the HiC-Pro output directly into .hic files via the hicpro2juicebox.sh shell script available rom the HiC-Pro authors: https://github.com/nservant/HiC-Pro/blob/master/doc/UTILS.md