search

asapdiscovery / asapdiscovery.github.io

3 stars 4 forks source link

Add link of protocols.io assay SARS-CoV-2 Mpro. #187

Closed maryhorsann closed 1 week ago

maryhorsann commented 4 months ago

Add link from protocols.io to an fluorescence dose response assay section of SARS-CoV-2 Mpro.

https://www.protocols.io/view/sars-cov-2-mpro-fluorescence-dose-response-81wgbye9nvpk/v4

jchodera commented 1 week ago

@maryhorsann : Can we refine the description of this protocol? It begins with:

"This is a functional, biochemical assay used to identify treatments for viral infectious disease that target SARS-COV-2 Main Protease (MPro)."

Instead, should it not say something like

"This biochemical assay measures the inhibition of protease activity of the SARS-CoV-2 main viral protease (Mpro), also known as the 3C-like protease (3CLpro). It is suitable for high-throughput dose-response measurements in a 384-well plates for supporting drug discovery efforts against this target."