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asrhou / NATMI

NATMI: Network Analysis Toolkit for the Multicellular Interactions
MIT License
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P values for ExtractEdges.py #45

Open saisomesh2594 opened 3 years ago

saisomesh2594 commented 3 years ago

Hi Rui,

I am wondering if there is any way to compute p-values for the edges extracted in the ExtractEdges.py ? Does that even make sense?

How would one go about doing so?

Thanks, Somesh

asrhou commented 3 years ago

Hi Somesh,

We think it does not make sense considering that a ligand/receptor can be expressed by multiple cell types. If you want to obtain p-values, you may want to try CellPhoneDB.

Cheers, Rui