Open jeromekelleher opened 2 years ago
we currently consider the simplest case, whereby multiple alleles are allowed at a given site but where mutation probabilities to each are equal.
It should be now easy to switch the emission probability matrix to support multiple alleles.
In the simplest case, the reference panel can contain values > 1. Initial version can assume that mutation rates among the k existing alleles are equal. We should keep the possibility open of providing arbitrary transition matrix between states.
May be as easy to do in the first pass as a kxk uniform transition matrix that we create, and then worry about making a parameter later.