auerbachs / BMDExpress-2

Software for analyzing high dimensional dose-response data
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Mac OSX vs. Windows: Difference in Results #5

Open RStainforth opened 5 years ago

RStainforth commented 5 years ago

I have encountered an issue when attempting a BMD analysis on the same example data set, but using BMDExpress 2.2 on different platforms; OSX 10.13.6 and Windows 10. I've attached the example data set below (it is 'example data 1.txt' as provided by the BMDExpress website).

The issue I observe is that on the OSX version of the software, none of the models (hill, power, linear, polyN, expN) appear to be applied/fit. On the Windows version, the models are applied. I've attached the two relevant .bm2 files from the OSX and Windows versions below into a compressed .zip file (bmdexpress_2p2_example_data_1.zip).

I've attached a comparison of the benchmark dose analysis panel for these two .bm2 project files. WINDOWS Version: bm2_example_data_1_WINDOWS

OSX Version: bm2_example_data_1_OSX

My understanding is that the OSX and Windows versions should produce only slightly different results due to floating point precision being different on the different platforms, but this appears to be a different issue; none of the model 'versions' seem to be recognised for the OSX version.

Let me know if any further information is required.

Thanks to anyone who can help.

bmdexpress_2p2_example_data_1.zip example data 1.txt

auerbachs commented 3 years ago

https://youtu.be/hKxs5YnhcgM