Closed csijcs closed 2 years ago
Hi,
This error generally arises when there is no covariance (i.e. no change within PC coordinates) between a pair or across a group of samples. I will suggest generating a chromosome-wise correlation table across the samples. This will help you to find the chromosome(s) which remained completely unchanged across the conditions that you're testing for. I will also try to run on a higher resolution Hi-C data like ~40Kb or ~10Kb. In some cases, the higher resolution leads to some covariance and will avoid the error.
I am able to run some samples without error, but I am currently getting an error for a particular group of samples when I run:
Rscript ~/dcHiC/dchicf.r --file BC005_input.txt --pcatype analyze --dirovwt T --diffdir BC005_100Kb
I get the error:Any idea what could be causing this and how to fix it?