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bartongroup / RATS

Relative Abundance of Transcripts: An R package for the detection of Differential Transcript isoform Usage.
MIT License
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Determining eligibility based on number of expressed isoforms #51

Closed fruce-ki closed 6 years ago

fruce-ki commented 6 years ago

The current filtering code determines if both conditions have only one expressed isoform and marks those as ineligible for testing.

However, that does not guarantee that the solo expressed isoform is the same one in both conditions. This means that binary switches of isoform can be erroneously missed when expression is all-or-nothing.