For example, using a window size of 3 we now model each kmer by the mean and dwell of the kmer and the kmers at +-1 from it - meaning our GMM has 6 variables. This should improve the separation of modified and unmodified kmers and might make single molecule predictions more accurate.
For example, using a window size of 3 we now model each kmer by the mean and dwell of the kmer and the kmers at +-1 from it - meaning our GMM has 6 variables. This should improve the separation of modified and unmodified kmers and might make single molecule predictions more accurate.