bartongroup / yanocomp

Yet another nanopore modification comparison tool
MIT License
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Model over multiple positions at once #1

Closed mparker2 closed 4 years ago

mparker2 commented 4 years ago

For example, using a window size of 3 we now model each kmer by the mean and dwell of the kmer and the kmers at +-1 from it - meaning our GMM has 6 variables. This should improve the separation of modified and unmodified kmers and might make single molecule predictions more accurate.